FATIMA, SITTI (2020) PERBADINGAN EFEKTIVITAS TERAPI PENGOBATAN PADA DEMAM TIFOID MENGGUNAKAN ANTIBIOTIK KLORAMPHENICOL, CEFOTAXIME DAN CEFTRIAXONE DI RAWAT INAP PUSKESMAS BANYUANYAR KABUPATEN SAMPANG. Masters thesis, UNIVERSITAS MA CHUNG.
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Abstract
The most common management of antibiotic therapy in typhoid fever is chloramphenicol and the use of third generation cephalosporins such as cefotaxime, ceftriaxone. Regarding the use of the three antibiotics, there has been no evaluation of the effectiveness of therapy for typhoid fever at the Banyuanyar Health Center. The Banyuanyar Health Center is one of the largest health centers in the Sampang district. Available inpatient services and typhoid fever is the 10 most common diseases in the inpatient Banyuanyar Health Center.The purpose of this study was to determine the effectiveness of treatment therapy using the antibiotics chloramphenicol, cefotaxime and ceftriaxone in typhoid fever patients based on a decrease in fever temperature, aboratory results and length of treatment. This research is included in quantitative research with retrospectiv data collection, namely research in the form of observation of past data, data collection was carried out for 6 months from October 2019 to March 2020. The study was carried out parametrically by looking at the effectiveness before and after dministration of antibiotics using a test. chi-square test, paired sample t-test and one way anova test for the length of treatment.The results obtained from the chi-square test of the gender variable obtained the value of sig.0,329> 0.05, age sig. 0,552 > 0,05 and weight value of sig.0,241 > 0,05 so that it is known that there is no significant relationship between sex, age and weight with the type of
antibiotic. To test the effectiveness of the three antibiotics, the paired sample t-test was used
because the conditions for using the test were data that were normally distributed and the variance of homogeneous data had been met previously. The effectiveness of the three
antibiotics from fever temperature 0.000 <0.05 This value indicates that there is a significant difference from the patient's temperature before being given antibiotics, from the laboratory results, the sig value. 0.000<0.05. This value indicates that there is a significant difference from
the patient's laboratory results before being given antibiotics. Based on the results of the effectiveness test on the length of stay with the one way anova test, the Sig value was obtained. 0.719 which means greater than 0.05 so it can be stated that there is no difference in hospitalization based on the three types of antibiotics.
The results of this study can be concluded that the three antibiotic therapies are both effective antibiotics used for the treatment of typhoid fever when viewed from the ability to reduce the patient's fever temperature and the patient's Tet Widal laboratory results.Keywords: Effectiveness, Antibiotics, Typhoid Fever
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | TUGAS AKHIR |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Fakultas Ilmu Kesehatan > S1 Farmasi |
| Depositing User: | Surya |
| Date Deposited: | 13 Feb 2025 02:46 |
| Last Modified: | 13 Feb 2025 02:46 |
| URI: | http://repository.machung.ac.id/id/eprint/847 |
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